Category Archives: Applied Research

“The two magic words of hemostasis: amplification and regulation”

Joost Meijers Professor Joost Meijers is manager of the Plasma Proteins department of the Research Division of Sanquin. He started his career at Utrecht University, became professor at the AMC Amsterdam and joined Sanquin in 2014. Besides doing research he committed himself to teaching and was involved in numerous committees in the field of hemostasis and fibrinolysis. He is currently chairman of the ISTH SSC Subcommittee on Factor XI and the Contact System, Secretary/Treasurer of the International Society on Fibrinolysis and Proteolysis, and is member of the Executive Board of the Dutch Thrombosis Foundation.

“I try to envisage how molecules interact with each other”

Theo Rispens Theo Rispens is group leader at the department of Immunopathology Research. His research topics cover all aspects of antibodies, from structure-function analysis of IVIg to regulation of antibody production. This includes immunogenicity of biologicals.

“A personalized approach to donation prevents deferrals and keeps the donor healthy.”

Katja van den HurkKatja van den Hurk works as a senior epidemiologist at the department of Donor Studies at Sanquin Blood Supply. Her main research topics are Donor characteristics and Donor health. Sanquin, by law the only blood bank in the Netherlands, has an extremely loyal donor population of about 2.5% of the Dutch population, that make approximately 800.000 donations per year. In the Netherlands the blood supply is dependent on voluntary non-remunerated donors.

“Hematopoietic stem cells walk on a narrow balance between leukemia and aging”

Marieke von Lindern Marieke von Lindern is head of the department of Hematopoiesis. Her department investigates the process by which mature peripheral blood cells are formed from the hematopoietic stem cell (HSC). Important topics are aging of stem cells and the culture and maturation of various blood cell types from progenitor cells, isolated from peripheral blood.

“We generate knowledge and insight”

Prof Peter Hordijk is working for Sanquin since 1997. He started as a staff member at the Department of Experimental Immunohematology. In 2005 he became head of the Molecular Cell Biology department. Hordijk is a specialist in the area of intracellular signaling in leukocyte transendothelial migration. The work of his group is focused on the role of small GTPases as well as specific cell adhesion molecules in the control of leukocyte and stem cell chemotaxis, leukocyte adhesion to endothelium and the modulation of endothelial integrity.