Category Archives: Basic Research

“The two magic words of hemostasis: amplification and regulation”

Joost Meijers Professor Joost Meijers is manager of the Plasma Proteins department of the Research Division of Sanquin. He started his career at Utrecht University, became professor at the AMC Amsterdam and joined Sanquin in 2014. Besides doing research he committed himself to teaching and was involved in numerous committees in the field of hemostasis and fibrinolysis. He is currently chairman of the ISTH SSC Subcommittee on Factor XI and the Contact System, Secretary/Treasurer of the International Society on Fibrinolysis and Proteolysis, and is member of the Executive Board of the Dutch Thrombosis Foundation.

“I try to envisage how molecules interact with each other”

Theo Rispens Theo Rispens is group leader at the department of Immunopathology Research. His research topics cover all aspects of antibodies, from structure-function analysis of IVIg to regulation of antibody production. This includes immunogenicity of biologicals.

“These are the fundamental questions that really need to be answered”

wolkers Monika Wolkers is a group leader at the Department of Hematopoiesis as from October 2010. Before she came to Sanquin she worked for the Netherlands Cancer Institute, the Academic Medical Center, Amsterdam, and the La Jolla Institute for Allergy and Immunology in the USA. Her research is mainly aimed at T cells and antigen presenting cells.

“We need to get to know these cells much better”

Carlijn Voermans started working for Sanquin in 1996 as a PhD student at the Department of Experimental Immunohematology (IHE) and obtained her PhD in 2001. In that same year she became head of the laboratory for Stem Cell Transplantation of Sanquin. After a one and halve year leave to the Duke University Medical Center in Durham as a Postdoc, she returned to Sanquin in 2006, again as head of the laboratory for Stem Cell Transplantation (now called Laboratory for Cell Therapy) and group leader within the department of IHE. She currently works as a group leader within the department of Hematopoiesis. The projects she and her group are working on are focused on the bone marrow micro-environment.

“We generate knowledge and insight”

Prof Peter Hordijk is working for Sanquin since 1997. He started as a staff member at the Department of Experimental Immunohematology. In 2005 he became head of the Molecular Cell Biology department. Hordijk is a specialist in the area of intracellular signaling in leukocyte transendothelial migration. The work of his group is focused on the role of small GTPases as well as specific cell adhesion molecules in the control of leukocyte and stem cell chemotaxis, leukocyte adhesion to endothelium and the modulation of endothelial integrity.