Category Archives: Clinical Research

“Hematopoietic stem cells walk on a narrow balance between leukemia and aging”

Marieke von Lindern Marieke von Lindern is head of the department of Hematopoiesis. Her department investigates the process by which mature peripheral blood cells are formed from the hematopoietic stem cell (HSC). Important topics are aging of stem cells and the culture and maturation of various blood cell types from progenitor cells, isolated from peripheral blood.

“Maybe, future research will bring us tailor made treatment”

Paula Ypma is a hematologist in The HagaZiekenhuis in The Hague for over ten years now. Although, during her study Ypma was never much involved in research, the drive to be part of a scientific study was still there. So, since two years now, she spends one day a week on research; a clinical trial study performed by Sanquin.

‘We still do not know it and therefore we need to study it’

kerkhoffs Jean-Louis Kerkhoffs is a hematologist in The HagaZiekenhuis in The Hague and a senior researcher at the Department of Clinical Transfusion Research at Sanquin as from 2004. In May 2012 he finished his PhD ‘Efficacy of platelet transfusions’. He is a specialist in the areas of platelet research, sickle cell disease and therapeutic aphaeresis.

“We need to get to know these cells much better”

Carlijn Voermans started working for Sanquin in 1996 as a PhD student at the Department of Experimental Immunohematology (IHE) and obtained her PhD in 2001. In that same year she became head of the laboratory for Stem Cell Transplantation of Sanquin. After a one and halve year leave to the Duke University Medical Center in Durham as a Postdoc, she returned to Sanquin in 2006, again as head of the laboratory for Stem Cell Transplantation (now called Laboratory for Cell Therapy) and group leader within the department of IHE. She currently works as a group leader within the department of Hematopoiesis. The projects she and her group are working on are focused on the bone marrow micro-environment.