“The two magic words of hemostasis: amplification and regulation”

Joost Meijers Professor Joost Meijers is manager of the Plasma Proteins department of the Research Division of Sanquin. He started his career at Utrecht University, became professor at the AMC Amsterdam and joined Sanquin in 2014. Besides doing research he committed himself to teaching and was involved in numerous committees in the field of hemostasis and fibrinolysis. He is currently chairman of the ISTH SSC Subcommittee on Factor XI and the Contact System, Secretary/Treasurer of the International Society on Fibrinolysis and Proteolysis, and is member of the Executive Board of the Dutch Thrombosis Foundation.

“I try to envisage how molecules interact with each other”

Theo Rispens Theo Rispens is group leader at the department of Immunopathology Research. His research topics cover all aspects of antibodies, from structure-function analysis of IVIg to regulation of antibody production. This includes immunogenicity of biologicals.

“A personalized approach to donation prevents deferrals and keeps the donor healthy.”

Katja van den HurkKatja van den Hurk works as a senior epidemiologist at the department of Donor Studies at Sanquin Blood Supply. Her main research topics are Donor characteristics and Donor health. Sanquin, by law the only blood bank in the Netherlands, has an extremely loyal donor population of about 2.5% of the Dutch population, that make approximately 800.000 donations per year. In the Netherlands the blood supply is dependent on voluntary non-remunerated donors.

“Hematopoietic stem cells walk on a narrow balance between leukemia and aging”

Marieke von Lindern Marieke von Lindern is head of the department of Hematopoiesis. Her department investigates the process by which mature peripheral blood cells are formed from the hematopoietic stem cell (HSC). Important topics are aging of stem cells and the culture and maturation of various blood cell types from progenitor cells, isolated from peripheral blood.

“This knowledge will be crucial to develop new storage strategies…”

Van Bruggen Robin van Bruggen started his career at Sanquin in 1998 as a PhD student. After his PhD and two post-doc projects, he is currently the group leader of the Red Blood Cell research group at the Laboratory of Blood Transfusion Technology.

“Maybe, future research will bring us tailor made treatment”

Paula Ypma is a hematologist in The HagaZiekenhuis in The Hague for over ten years now. Although, during her study Ypma was never much involved in research, the drive to be part of a scientific study was still there. So, since two years now, she spends one day a week on research; a clinical trial study performed by Sanquin.

‘We still do not know it and therefore we need to study it’

kerkhoffs Jean-Louis Kerkhoffs is a hematologist in The HagaZiekenhuis in The Hague and a senior researcher at the Department of Clinical Transfusion Research at Sanquin as from 2004. In May 2012 he finished his PhD ‘Efficacy of platelet transfusions’. He is a specialist in the areas of platelet research, sickle cell disease and therapeutic aphaeresis.

“These are the fundamental questions that really need to be answered”

wolkers Monika Wolkers is a group leader at the Department of Hematopoiesis as from October 2010. Before she came to Sanquin she worked for the Netherlands Cancer Institute, the Academic Medical Center, Amsterdam, and the La Jolla Institute for Allergy and Immunology in the USA. Her research is mainly aimed at T cells and antigen presenting cells.

“We need to get to know these cells much better”

Carlijn Voermans started working for Sanquin in 1996 as a PhD student at the Department of Experimental Immunohematology (IHE) and obtained her PhD in 2001. In that same year she became head of the laboratory for Stem Cell Transplantation of Sanquin. After a one and halve year leave to the Duke University Medical Center in Durham as a Postdoc, she returned to Sanquin in 2006, again as head of the laboratory for Stem Cell Transplantation (now called Laboratory for Cell Therapy) and group leader within the department of IHE. She currently works as a group leader within the department of Hematopoiesis. The projects she and her group are working on are focused on the bone marrow micro-environment.